Statins: The sign of ‘life-threatening’ muscle damage that can show up in the extremities


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“Swelling may be due to either muscle swelling, which would be non-pitting (does not indent when pressure is applied) and can and can appear either at presentation or after rehydration.”

Alternatively, added Doctor Shefner, swelling in the extremities could be caused by peripheral oedema, which would be pitting and occurs with rehydration.

He added: “Limb induration is occasionally present. Skin changes of ischaemic tissue injury, such as discolouration or blisters, may also be seen but are present in less than 10 percent of patients.”

The condition, or other milder forms of muscle inflammation from statins, can be diagnosed with a blood test measuring blood levels of creatinine kinase.

READ MORE: Statins: ‘Check with your doctor’ if you notice a sign around the eyes


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